ciliary basal body docking, anchoring of the basal body to the plasma membrane
Alternate IDs
None
Definition
The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane.
Source:Reactome:R-HSA-5620912.1,
PMID:23530209,
GOC:cilia,
PMID:25686250,
PMID:23348840,
PMID:13978319,
PMID:26981235
Comment
Basal bodies in jawed vertebrates appear to first attach to a ciliary vesicle. It is unclear how specific this is to jawed vertebrates or if other organisms also employ this sequence. Some species like Giardia intestinalis do not relocate their basal bodies to the plasma membrane, but have their axonemes extend through the cytosol to then protrude out of the cell to form flagella.