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ventral disc

Term Information

Accession
GO:0097597
Name
ventral disc
Ontology
cellular_component
Synonyms
ventral adhesive disc, adhesive disc, ventral disk
Alternate IDs
None
Definition
Specialized organelle found in Giardia species (trophozoite stage) and characterized by a spiral array of microtubules and microtubule-associated structures including dorsal microribbons and crossbridges. The edge of the ventral disc narrows into a lateral crest. The ventral disk mediates mechanical attachment of the trophozoite to the host's intestinal wall, and contains the contractile proteins actinin, alpha-actinin, myosin, and tropomyosin working towards contraction of the disk involved in adherence. Source: GOC:giardia, PMID:11432808, PMID:5961344, PMID:4777416, ISBN:9780124260207
Comment
Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.
History
See term history for GO:0097597 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of ventral disc (GO:0097597)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ventral disc [BFO:0000051 relation] BFO:0000051  ventral disc dorsal microribbon (GO:0097594)
ventral disc [BFO:0000051 relation] BFO:0000051  ventral disc lateral crest (GO:0097591)
ventral disc [BFO:0000051 relation] BFO:0000051  ventral disc overlap zone (GO:0097592)
ventral disc [BFO:0000051 relation] BFO:0000051  ventral disc crossbridge (GO:0097595)
ventral disc [is_a relation] is_a  intracellular non-membrane-bounded organelle (GO:0043232)
Children of ventral disc (GO:0097597)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ventral disc supernumerary microtubule array (GO:0097596) [BFO:0000050 relation] BFO:0000050  ventral disc
ventral disc microtubule array (GO:0097593) [BFO:0000050 relation] BFO:0000050  ventral disc
ventral disc dorsal microribbon (GO:0097594) [BFO:0000050 relation] BFO:0000050  ventral disc
ventral disc overlap zone (GO:0097592) [BFO:0000050 relation] BFO:0000050  ventral disc
ventral disc lateral crest (GO:0097591) [BFO:0000050 relation] BFO:0000050  ventral disc
ventral disc crossbridge (GO:0097595) [BFO:0000050 relation] BFO:0000050  ventral disc
None.