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ruffle assembly

Term Information

Accession
GO:0097178
Name
ruffle assembly
Ontology
biological_process
Synonyms
membrane ruffle formation, membrane ruffling
Alternate IDs
None
Definition
The aggregation, arrangement and bonding together of a set of components to form a ruffle, a projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. The formation of ruffles (also called membrane ruffling) is thought to be controlled by a group of enzymes known as Rho GTPases, specifically RhoA, Rac1 and cdc42. Source: http:en.wikipedia.org/wiki/Membrane_ruffling, PMID:12556481, GOC:yaf
Comment
None
History
See term history for GO:0097178 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of ruffle assembly (GO:0097178)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ruffle assembly [is_a relation] is_a  ruffle organization (GO:0031529)
ruffle assembly [is_a relation] is_a  plasma membrane bounded cell projection assembly (GO:0120031)
Children of ruffle assembly (GO:0097178)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of ruffle assembly (GO:1900028) [RO:0002212 relation] RO:0002212  ruffle assembly
positive regulation of ruffle assembly (GO:1900029) [RO:0002213 relation] RO:0002213  ruffle assembly
regulation of ruffle assembly (GO:1900027) [RO:0002211 relation] RO:0002211  ruffle assembly
None.