Term Information

Accession
GO:0086099
Name
phospholipase C-activating angiotensin-activated signaling pathway involved in heart process
Ontology
biological_process
Synonyms
Gq-coupled angiotensin receptor signaling pathway involved in heart process, PLC-activating angiotensin receptor signaling pathway involved in heart process, angiotensin receptor signaling pathway via activation of phospholipase C involved in heart process, cardiac angiotensin receptor signaling pathway via activation of PLC, phospholipase C-activating angiotensin-mediated signaling pathway involved in heart process
Alternate IDs
None
Definition
An angiotensin-mediated signaling pathway that contributes to a circulatory system process carried out by the heart, where the activated receptor transmits the signal via Gq-mediated activation of phospholipase C (PLC). PLC hydrolyses phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers inositol-1,4,5,-triphosphate (IP3) and diacylglycerol (DAG). DAG activates protein kinase C (PKC), whilst IP3 binds intracellular receptors to induce the release of Ca2+ from intracellular stores. Source: PMID:17376402, GOC:BHF, GOC:mtg_cardiac_conduct_nov11
Comment
None
History
See term history for GO:0086099 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of phospholipase C-activating angiotensin-activated signaling pathway involved in heart process (GO:0086099)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
phospholipase C-activating angiotensin-activated signaling pathway involved in heart process [BFO:0000050 relation] BFO:0000050  heart process (GO:0003015)
phospholipase C-activating angiotensin-activated signaling pathway involved in heart process [is_a relation] is_a  phospholipase C-activating angiotensin-activated signaling pathway (GO:0086097)
phospholipase C-activating angiotensin-activated signaling pathway involved in heart process [is_a relation] is_a  angiotensin-activated signaling pathway involved in heart process (GO:0086098)

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