Term Information

Accession
GO:0086096
Name
adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process
Ontology
biological_process
Synonyms
G-inhibitory-coupled Beta2AR signaling pathway involved in heart process, Gi-coupled Beta2-AR signaling pathway involved in heart process, Gi-coupled adrenergic receptor signaling pathway involved in heart process, cardiac adrenergic receptor signaling pathway via inhibition of adenylate cyclase activity
Alternate IDs
None
Definition
An adenylate cyclase-inhibiting adrenergic receptor signaling pathway which contributes to a circulatory system process carried out by the heart. Source: GOC:BHF, PMID:10571541, GOC:mtg_cardiac_conduct_nov11
Comment
Although Beta1-adrenergic receptors couple exclusively to the Gs protein, Beta2-adrenergic receptors couple to both Gs and Gi proteins. Coupling to Gi proteins may localize the Gs-mediated signaling.
History
See term history for GO:0086096 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process (GO:0086096)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process [is_a relation] is_a  adenylate cyclase-inhibiting adrenergic receptor signaling pathway (GO:0071881)
adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process [BFO:0000050 relation] BFO:0000050  heart process (GO:0003015)
adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process [is_a relation] is_a  G protein-coupled receptor signaling pathway involved in heart process (GO:0086103)
Children of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process (GO:0086096)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process (GO:0140195) [RO:0002213 relation] RO:0002213  adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process
negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process (GO:0140194) [RO:0002212 relation] RO:0002212  adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process
regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process (GO:0140193) [RO:0002211 relation] RO:0002211  adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process
None.