Planteome: Term Details for "NLRP3 inflammasome complex" (GO:0072559)

Accession: GO:0072559
Name: NLRP3 inflammasome complex
Ontology: cellular_component
Synonyms: NALP3 inflammasome complex
Alternate IDs: None
Definition: An inflammasome complex that consists of three components, NLRP3 (NALP3), PYCARD and caspase-1. It is activated upon exposure to whole pathogens, as well as a number of structurally diverse pathogen- and danger-associated molecular patterns (PAMPs and DAMPs) and environmental irritants. Whole pathogens demonstrated to activate the NLRP3 inflammasome complex include the fungi Candida albicans and Saccharomyces cerevisiae, bacteria that produce pore-forming toxins, including Listeria monocytogenes and Staphylococcus aureus, and viruses such as Sendai virus, adenovirus, and influenza virus. Source: PMID:20303873, GOC:BHF, GOC:add, GOC:vp
Comment: None
History: See term history for GO:0072559 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to NLRP3 inflammasome complex.; Link to all direct and indirect annotations to NLRP3 inflammasome complex.; Link to all direct and indirect annotations download (limited to first 10,000) for NLRP3 inflammasome complex.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

subject	relation	object
NLRP3 inflammasome complex	is_a	canonical inflammasome complex (GO:0061702)

This term has no children.

NLRP3 inflammasome complex