Term Information

Accession
GO:0071986
Name
Ragulator complex
Ontology
cellular_component
Synonyms
MAPKSP1/ROBLD3/C11orf59 complex, Rag GEF, EGO complex, EGO-GSE complex, GSE complex, GTPase-containing complex for Gap1p sorting in the endosome
Alternate IDs
GO:0034449, GO:0034448
Definition
A vacuolar membrane-anchored guanine nucleotide exchange factor (GEF) complex for the Rag GTPases (Gtr1-Gtr2 GTPase complex GO:1990131) in TORC1 signalling pathway. In human, Ragulator is comprised of the membrane anchor subunit LAMTOR1 (Meh1p in S. cerevisiae, Lam1 in S. pombe), a GEF subunit LAMTOR2 ( Slm4 in S. cerevisiae , Lam2 in S. pombe ) , LAMTOR3 (no S. cerevisiae ortholog identified, Lam3 in S. pombe) , LAMTOR4 (no S. cerevisiae ortholog identified, Lam4 in S. pombe), and LAMTOR5 (no S. cerevisiae or S. pombe ortholog identified). Source: PMID:29199950, PMID:16732272, GOC:vw, PMID:15989961, PMID:19748353, PMID:22980980, PMID:19177150, PMID:20381137
Comment
None
History
See term history for GO:0071986 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
Parents of Ragulator complex (GO:0071986)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
Ragulator complex [is_a relation] is_a  guanyl-nucleotide exchange factor complex (GO:0032045)
Ragulator complex [is_a relation] is_a  membrane protein complex (GO:0098796)
Ragulator complex [BFO:0000050 relation] BFO:0000050  vacuolar membrane (GO:0005774)

This term has no children.

None.