Planteome: Term Details for "microprocessor complex" (GO:0070877)

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Term Information

Accession: GO:0070877
Name: microprocessor complex
Ontology: cellular_component
Synonyms: None
Alternate IDs: None
Definition: A protein complex that binds to heme and to pri-miRNAs, and is required for the formation of a pre-microRNA (pre-miRNA), the initial step of microRNA (miRNA) biogenesis. The complex is composed of the double-stranded-RNA-specific RNase Drosha (also called RNASEN) and the RNA-binding protein DGCR8 (heme-free or heme-bound forms). Within the complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs RNASEN/Drosha to cleave the 3' and 5' strands of a stem-loop to release hairpin-shaped pre-miRNAs. Source: PMID:16963499, PMID:17159994
Comment: None
History: See term history for GO:0070877 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to microprocessor complex.; Link to all direct and indirect annotations to microprocessor complex.; Link to all direct and indirect annotations download (limited to first 10,000) for microprocessor complex.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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GO:0005575 cellular_component
GO:0110165 cellular anatomical entity
GO:0005622 intracellular anatomical structure
GO:0043226 organelle
GO:0032991 protein-containing complex
GO:1902494 catalytic complex
GO:0043229 intracellular organelle
GO:0140535 intracellular protein-containing complex
GO:0043227 membrane-bounded organelle
GO:1905348 endonuclease complex
GO:0043231 intracellular membrane-bounded organelle
GO:1902555 endoribonuclease complex
GO:0005634 nucleus
GO:0140513 nuclear protein-containing complex
GO:1903095 ribonuclease III complex
GO:0070877 microprocessor complex

Parents of microprocessor complex (GO:0070877)

subject	relation	object
microprocessor complex	is_a	ribonuclease III complex (GO:1903095)
microprocessor complex	is_a	nuclear protein-containing complex (GO:0140513)

This term has no children.

microprocessor complex

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Parents of microprocessor complex (GO:0070877)

None.