Planteome logo

interleukin-35 complex

Term Information

Accession
GO:0070745
Name
interleukin-35 complex
Ontology
cellular_component
Synonyms
IL-35 complex, EBI3, IL12A, p35
Alternate IDs
None
Definition
A protein complex that is composed of an interleukin-12 alpha subunit (p35, product of the IL12A gene) and an EBI3 subunit and is secreted into the extracellular space. Source: GOC:add, PMID:19161429, PMID:19161428
Comment
Note that this heterodimeric cytokine utilizes the same IL-12p35 subunit as its alpha chain as IL-12 uses and the same EBI3 subunit (product of EBI3, Epstein-Barr virus induced gene 3) as its beta chain as IL-27 uses. IL-35 requires both subunits -- there is no separate IL35 gene.
History
See term history for GO:0070745 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
Parents of interleukin-35 complex (GO:0070745)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
interleukin-35 complex [is_a relation] is_a  protein-containing complex (GO:0032991)
interleukin-35 complex [BFO:0000050 relation] BFO:0000050  extracellular space (GO:0005615)

This term has no children.

None.