A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex).
Source:
GOC:ab,
GOC:mah,
PMID:18799622
Comment
Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.