Term Information

Accession
GO:0070533
Name
BRCA1-C complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A protein complex that contains the BRCA1-BARD1 heterodimer, CtIP and Mre11/Rad50/NBS1 (M/R/N) complex, and binds to DNA at DNA damage sites. BRCA1-C binding ta damaged DNA is required for DNA damage-induced Chk1 phosphorylation and the G2/M transition checkpoint. Source: PMID:16391231, PMID:15485915, GOC:mah
Comment
None
History
See term history for GO:0070533 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of BRCA1-C complex (GO:0070533)
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BRCA1-C complex [is_a relation] is_a  nuclear protein-containing complex (GO:0140513)

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None.