Planteome: Term Details for "shelterin complex" (GO:0070187)

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Term Information

Accession: GO:0070187
Name: shelterin complex
Ontology: cellular_component
Synonyms: Pot1 complex, Pot1-Tpz1 complex, telosome
Alternate IDs: None
Definition: A nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase. The complex is known to contain TERF1, TERF2, POT1, RAP1, TINF2 and ACD in mammalian cells, and Pot1, Tpz1, Rap1, Rif1, Rif2 and Taz1 in Saccharomyces. Taz1 and Rap1 (or their mammalian equivalents) form a dsDNA-binding subcomplex, Pot1 and Tpz1 form an ssDNA-binding subcomplex, and the two subcomplexes are bridged by Poz1, which acts as an effector molecule along with Ccq1. Source: PMID:18828880, GOC:expert_mf, GOC:vw, GOC:mah
Comment: None
History: See term history for GO:0070187 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to shelterin complex.; Link to all direct and indirect annotations to shelterin complex.; Link to all direct and indirect annotations download (limited to first 10,000) for shelterin complex.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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GO:0043226 organelle
GO:0043229 intracellular organelle
GO:0043228 non-membrane-bounded organelle
GO:0110165 cellular anatomical entity
GO:0005575 cellular_component
GO:0043232 intracellular non-membrane-bounded organelle
GO:0005694 chromosome
GO:0005622 intracellular anatomical structure
GO:0098687 chromosomal region
GO:0043227 membrane-bounded organelle
GO:0000781 chromosome, telomeric region
GO:0043231 intracellular membrane-bounded organelle
GO:0032991 protein-containing complex
GO:0140445 chromosome, telomeric repeat region
GO:0005634 nucleus
GO:0032993 protein-DNA complex
GO:0140513 nuclear protein-containing complex
GO:0000782 telomere cap complex
GO:0000783 nuclear telomere cap complex
GO:0070187 shelterin complex

Parents of shelterin complex (GO:0070187)

subject	relation	object
shelterin complex	is_a	nuclear telomere cap complex (GO:0000783)

This term has no children.

shelterin complex

Term Information

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Parents of shelterin complex (GO:0070187)

None.