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ATG2-ATG18 complex

Term Information

Accession
GO:0062079
Name
ATG2-ATG18 complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A protein complex essential for autophagy during nutrient deprivation, a catabolic process that sequesters undesired cellular material into autophagosomes for delivery to lysosomes for degradation. Contributes to nutrition homeostasis and damage control in eukaryotic cells. Functions at a late step of autophagosome formation for efficient completion of sequestration, probably through facilitating recruitment of ATG8-phosphatidylethanolamine (PE) to the preautophagosomal structure (PAS) and/or its protection from deconjugation by ATG4. Composed of ATG2 and ATG18 in Saccharomyces cerevisiae. Source: PMID:23230146, GOC:bhm
Comment
None
History
See term history for GO:0062079 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of ATG2-ATG18 complex (GO:0062079)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ATG2-ATG18 complex [BFO:0000050 relation] BFO:0000050  phagophore assembly site membrane (GO:0034045)
ATG2-ATG18 complex [is_a relation] is_a  membrane protein complex (GO:0098796)

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None.