Term Information

Accession
GO:0060072
Name
large conductance calcium-activated potassium channel activity
Ontology
molecular_function
Synonyms
BK KCa channel activity, BK calcium-activated potassium channel activity, large conductance KCa channel activity, BK channel activity
Alternate IDs
GO:0022895
Definition
Enables the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. Source: GOC:mtg_transport, ISBN:0815340729, PMID:17115074
Comment
None
History
See term history for GO:0060072 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of large conductance calcium-activated potassium channel activity (GO:0060072)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
large conductance calcium-activated potassium channel activity [is_a relation] is_a  calcium-activated potassium channel activity (GO:0015269)
Children of large conductance calcium-activated potassium channel activity (GO:0060072)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of large conductance calcium-activated potassium channel activity (GO:1902608) [RO:0002213 relation] RO:0002213  large conductance calcium-activated potassium channel activity
negative regulation of large conductance calcium-activated potassium channel activity (GO:1902607) [RO:0002212 relation] RO:0002212  large conductance calcium-activated potassium channel activity
regulation of large conductance calcium-activated potassium channel activity (GO:1902606) [RO:0002211 relation] RO:0002211  large conductance calcium-activated potassium channel activity
None.