Term Information

Accession
GO:0052822
Name
DNA-3-methylguanine glycosylase activity
Ontology
molecular_function
Synonyms
3-methylguanine DNA glycosylase I, DNA glycosidase I activity, deoxyribonucleate 3-methylguanine glycosidase I, alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)
Alternate IDs
None
Definition
Catalysis of the reaction: DNA containing 3-methylguanine + H2O = DNA with abasic site + 3-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylguanine and the deoxyribose sugar to remove the 3-methylguanine, leaving an abasic site. Source: PMID:9224623, PMID:10872450, EC:3.2.2.21, GOC:elh
Comment
None
History
See term history for GO:0052822 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of DNA-3-methylguanine glycosylase activity (GO:0052822)
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DNA-3-methylguanine glycosylase activity [is_a relation] is_a  DNA-3-methylbase glycosylase activity (GO:0043733)

This term has no children.

EC
3.2.2.21
MetaCyc
3.2.2.21-RXN