Term Information

Accession
GO:0051880
Name
G-quadruplex DNA binding
Ontology
molecular_function
Synonyms
G quadruplex DNA binding, G quartet DNA binding, G-DNA binding, G-quartet DNA binding, quadruplex DNA binding, tetraplex DNA binding, G quartet binding, G-quartet binding
Alternate IDs
None
Definition
Binding to G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome. Source: PMID:16142245, PMID:9512530
Comment
None
History
See term history for GO:0051880 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
Parents of G-quadruplex DNA binding (GO:0051880)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
G-quadruplex DNA binding [is_a relation] is_a  DNA binding (GO:0003677)
Children of G-quadruplex DNA binding (GO:0051880)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of G-quadruplex DNA binding (GO:1905494) [RO:0002212 relation] RO:0002212  G-quadruplex DNA binding
regulation of G-quadruplex DNA binding (GO:1905493) [RO:0002211 relation] RO:0002211  G-quadruplex DNA binding
positive regulation of G-quadruplex DNA binding (GO:1905495) [RO:0002213 relation] RO:0002213  G-quadruplex DNA binding
telomeric G-quadruplex DNA binding (GO:0061849) [is_a relation] is_a  G-quadruplex DNA binding
None.