Term Information

Accession
GO:0051880
Name
G-quadruplex DNA binding
Ontology
molecular_function
Synonyms
G quadruplex DNA binding, G quartet DNA binding, G-DNA binding, G-quartet DNA binding, quadruplex DNA binding, tetraplex DNA binding, G quartet binding, G-quartet binding
Alternate IDs
None
Definition
Binding to G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome. Source: PMID:16142245, PMID:9512530
Comment
None
History
See term history for GO:0051880 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of G-quadruplex DNA binding (GO:0051880)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
G-quadruplex DNA binding [is_a relation] is_a  DNA binding (GO:0003677)
Children of G-quadruplex DNA binding (GO:0051880)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of G-quadruplex DNA binding (GO:1905494) [RO:0002212 relation] RO:0002212  G-quadruplex DNA binding
telomeric G-quadruplex DNA binding (GO:0061849) [is_a relation] is_a  G-quadruplex DNA binding
regulation of G-quadruplex DNA binding (GO:1905493) [RO:0002211 relation] RO:0002211  G-quadruplex DNA binding
positive regulation of G-quadruplex DNA binding (GO:1905495) [RO:0002213 relation] RO:0002213  G-quadruplex DNA binding
None.