Planteome logo

leukocyte tethering or rolling

Term Information

Accession
GO:0050901
Name
leukocyte tethering or rolling
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
Transient adhesive interactions between leukocytes and endothelial cells lining blood vessels. Carbohydrates on circulating leukocytes bind selectins on the vessel wall causing the leukocytes to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between selectins and their ligands. Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissue damage or infection). Source: PMID:8600538, PMID:7507411, ISBN:0781735149, PMID:14680625, GOC:bf, Wikipedia:Leukocyte_extravasation, PMID:14708592
Comment
None
History
See term history for GO:0050901 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
Parents of leukocyte tethering or rolling (GO:0050901)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
leukocyte tethering or rolling [BFO:0000050 relation] BFO:0000050  cellular extravasation (GO:0045123)
leukocyte tethering or rolling [is_a relation] is_a  leukocyte adhesion to vascular endothelial cell (GO:0061756)
Children of leukocyte tethering or rolling (GO:0050901)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of leukocyte tethering or rolling (GO:1903237) [RO:0002212 relation] RO:0002212  leukocyte tethering or rolling
regulation of leukocyte tethering or rolling (GO:1903236) [RO:0002211 relation] RO:0002211  leukocyte tethering or rolling
positive regulation of leukocyte tethering or rolling (GO:1903238) [RO:0002213 relation] RO:0002213  leukocyte tethering or rolling
None.