Term Information

Accession
GO:0048291
Name
isotype switching to IgG isotypes
Ontology
biological_process
Synonyms
class switching to IgG isotypes, isotype switch recombination to IgG isotypes
Alternate IDs
None
Definition
The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgG isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgG constant region gene segments in the immunoglobulin heavy chain locus. Source: PMID:2113175, PMID:9186655, ISBN:0781735149, PMID:12370374
Comment
None
History
See term history for GO:0048291 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of isotype switching to IgG isotypes (GO:0048291)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
isotype switching to IgG isotypes [is_a relation] is_a  isotype switching (GO:0045190)
Children of isotype switching to IgG isotypes (GO:0048291)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of isotype switching to IgG isotypes (GO:0048304) [RO:0002213 relation] RO:0002213  isotype switching to IgG isotypes
negative regulation of isotype switching to IgG isotypes (GO:0048303) [RO:0002212 relation] RO:0002212  isotype switching to IgG isotypes
regulation of isotype switching to IgG isotypes (GO:0048302) [RO:0002211 relation] RO:0002211  isotype switching to IgG isotypes
None.