Term Information

Accession
GO:0046820
Name
4-amino-4-deoxychorismate synthase activity
Ontology
molecular_function
Synonyms
ADC synthase activity, PabB activity, aminodeoxychorismate synthase activity, chorismate:L-glutamine amido-ligase activity, p-aminobenzoate synthetase, para-aminobenzoic acid (PABA) synthase, para-aminobenzoic acid synthase activity
Alternate IDs
None
Definition
Catalysis of the reaction: L-glutamine + chorismate = 4-amino-4-deoxychorismate + L-glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); the first is a glutaminase which yields ammonia from glutamine, releasing glutamate. The ammonia is used by the second activity which catalyzes the amination of chorismate to form 4-amino-4-deoxychorismate. Source: EC:2.6.1.85, RHEA:11672
Comment
Note that the name 'para-aminobenzoic acid synthase' was initially given to the 'aminodeoxychorismate synthase' activity before the additional 4-amino-4-deoxychorismate lyase activity was discovered. It is the lyase activity that actually produces para-aminobenzoic acid from 4-amino-4-deoxychorismate.
History
See term history for GO:0046820 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
Parents of 4-amino-4-deoxychorismate synthase activity (GO:0046820)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
4-amino-4-deoxychorismate synthase activity [is_a relation] is_a  transaminase activity (GO:0008483)

This term has no children.

EC
2.6.1.85
KEGG_REACTION
R01716
MetaCyc
PABASYN-RXN
RHEA
11672