Planteome: Term Details for "T-helper 1 cell differentiation" (GO:0045063)

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Term Information

Accession: GO:0045063
Name: T-helper 1 cell differentiation
Ontology: biological_process
Synonyms: T-helper 1 cell development
Alternate IDs: None
Definition: The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma. Source: CL:0000545, GOC:ebc
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
History: See term history for GO:0045063 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to T-helper 1 cell differentiation.; Link to all direct and indirect annotations to T-helper 1 cell differentiation.; Link to all direct and indirect annotations download (limited to first 10,000) for T-helper 1 cell differentiation.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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GO:0008150 biological_process
GO:0032502 developmental process
GO:0048856 anatomical structure development
GO:0030154 cell differentiation
GO:0048869 cellular developmental process
GO:0009987 cellular process
GO:0048468 cell development
GO:0002376 immune system process
GO:0032501 multicellular organismal process
GO:0001775 cell activation
BFO:0000001 entity
GO:0030097 hemopoiesis
GO:0002252 immune effector process
GO:0006955 immune response
BFO:0000003 occurrent
GO:0002263 cell activation involved in immune response
GO:0045321 leukocyte activation
GO:0002521 leukocyte differentiation
GO:0002366 leukocyte activation involved in immune response
GO:0046649 lymphocyte activation
GO:1903131 mononuclear cell differentiation
BFO:0000015 process
GO:0002285 lymphocyte activation involved in immune response
GO:0030098 lymphocyte differentiation
GO:0042110 T cell activation
GO:0046631 alpha-beta T cell activation
GO:0050896 response to stimulus
GO:0002286 T cell activation involved in immune response
GO:0030217 T cell differentiation
GO:0002287 alpha-beta T cell activation involved in immune response
GO:0046632 alpha-beta T cell differentiation
GO:0035710 CD4-positive, alpha-beta T cell activation
GO:0002292 T cell differentiation involved in immune response
GO:0002250 adaptive immune response
GO:0002293 alpha-beta T cell differentiation involved in immune response
GO:0043367 CD4-positive, alpha-beta T cell differentiation
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response
GO:0042088 T-helper 1 type immune response
GO:0042093 T-helper cell differentiation
GO:0045063 T-helper 1 cell differentiation
GO:0045626 negative regulation of T-helper 1 cell differentiation
GO:0045627 positive regulation of T-helper 1 cell differentiation
GO:0045625 regulation of T-helper 1 cell differentiation
GO:0002296 T-helper 1 cell lineage commitment

Parents of T-helper 1 cell differentiation (GO:0045063)

subject	relation	object
T-helper 1 cell differentiation	BFO:0000050	T-helper 1 type immune response (GO:0042088)
T-helper 1 cell differentiation	is_a	T-helper cell differentiation (GO:0042093)

Children of T-helper 1 cell differentiation (GO:0045063)

subject	relation	object
T-helper 1 cell lineage commitment (GO:0002296)	BFO:0000050	T-helper 1 cell differentiation
negative regulation of T-helper 1 cell differentiation (GO:0045626)	RO:0002212	T-helper 1 cell differentiation
positive regulation of T-helper 1 cell differentiation (GO:0045627)	RO:0002213	T-helper 1 cell differentiation
regulation of T-helper 1 cell differentiation (GO:0045625)	RO:0002211	T-helper 1 cell differentiation

T-helper 1 cell differentiation

Term Information

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Parents of T-helper 1 cell differentiation (GO:0045063)

Children of T-helper 1 cell differentiation (GO:0045063)

None.