Term Information

Accession
GO:0045048
Name
protein insertion into ER membrane
Ontology
biological_process
Synonyms
integral ER membrane protein localization, integral ER membrane protein positioning, localization of protein in ER membrane, positioning of protein in ER membrane, protein insertion into endoplasmic reticulum membrane, protein-ER insertion, protein-endoplasmic reticulum insertion
Alternate IDs
None
Definition
The process that results in incorporation of a protein into an endoplasmic reticulum (ER) membrane. It depends on specific topogenic sequences of amino acids that ensure that a protein acquires the proper orientation during its insertion into the ER membrane. Source: ISBN:0716731363
Comment
None
History
See term history for GO:0045048 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of protein insertion into ER membrane (GO:0045048)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
protein insertion into ER membrane [is_a relation] is_a  protein insertion into membrane (GO:0051205)
protein insertion into ER membrane [BFO:0000050 relation] BFO:0000050  endoplasmic reticulum organization (GO:0007029)
protein insertion into ER membrane [BFO:0000050 relation] BFO:0000050  protein localization to organelle (GO:0033365)
Children of protein insertion into ER membrane (GO:0045048)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
protein insertion into ER membrane by N-terminal cleaved signal sequence (GO:0045049) [is_a relation] is_a  protein insertion into ER membrane
protein insertion into ER membrane by internal uncleaved signal-anchor sequence (GO:0045051) [is_a relation] is_a  protein insertion into ER membrane
protein insertion into ER membrane by GPI attachment sequence (GO:0045052) [is_a relation] is_a  protein insertion into ER membrane
tail-anchored membrane protein insertion into ER membrane (GO:0071816) [is_a relation] is_a  protein insertion into ER membrane
multi-pass transmembrane protein insertion into ER membrane (GO:0160063) [is_a relation] is_a  protein insertion into ER membrane
protein insertion into ER membrane by stop-transfer membrane-anchor sequence (GO:0045050) [is_a relation] is_a  protein insertion into ER membrane
None.