Term Information

Accession
GO:0043626
Name
PCNA complex
Ontology
cellular_component
Synonyms
PCNA homotrimer, proliferating cell nuclear antigen complex, sliding clamp
Alternate IDs
None
Definition
A protein complex composed of three identical PCNA monomers, each comprising two similar domains, which are joined in a head-to-tail arrangement to form a homotrimer. Forms a ring-like structure in solution, with a central hole sufficiently large to accommodate the double helix of DNA. Originally characterized as a DNA sliding clamp for replicative DNA polymerases and as an essential component of the replisome, and has also been shown to be involved in other processes including Okazaki fragment processing, DNA repair, translesion DNA synthesis, DNA methylation, chromatin remodeling and cell cycle regulation. Source: PMID:12829735, GOC:jl
Comment
None
History
See term history for GO:0043626 at QuickGO
Subset
None
Feedback
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Parents of PCNA complex (GO:0043626)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
PCNA complex [is_a relation] is_a  DNA polymerase processivity factor complex (GO:0044796)

This term has no children.

None.