Term Information

Accession
GO:0043396
Name
corticotropin-releasing hormone secretion
Ontology
biological_process
Synonyms
CRF secretion, CRH secretion, corticotropin-releasing factor secretion
Alternate IDs
None
Definition
The regulated release of corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. CRH is produced by the hypothalamus and stimulates corticotropic cells of the anterior lobe of the pituitary to produce corticotropic hormone (CTH) and other biologically active substances e.g. 2-endorphin, release of CRH is affected by serum levels of cortisol, by stress and by the sleep/wake cycle. Source: GOC:go_curators, PMID:11027914
Comment
None
History
See term history for GO:0043396 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of corticotropin-releasing hormone secretion (GO:0043396)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
corticotropin-releasing hormone secretion [is_a relation] is_a  peptide hormone secretion (GO:0030072)
Children of corticotropin-releasing hormone secretion (GO:0043396)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of corticotropin-releasing hormone secretion (GO:0051465) [RO:0002212 relation] RO:0002212  corticotropin-releasing hormone secretion
positive regulation of corticotropin-releasing hormone secretion (GO:0051466) [RO:0002213 relation] RO:0002213  corticotropin-releasing hormone secretion
regulation of corticotropin-releasing hormone secretion (GO:0043397) [RO:0002211 relation] RO:0002211  corticotropin-releasing hormone secretion
None.