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neurotrophin binding

Term Information

Accession
GO:0043121
Name
neurotrophin binding
Ontology
molecular_function
Synonyms
neurotrophic factor binding, neurotrophin TRK receptor activity, neurotrophin TRKA receptor activity, neurotrophin TRKB receptor activity, neurotrophin TRKC receptor activity, NT 4/5 binding, NT-3 binding, NT-4 binding, NT-4/5 binding, NT-5 binding, NT3 binding, NT4 binding, NT5 binding, neurotrophin 3 binding, neurotrophin 4/5 binding, neurotrophin-3 binding, neurotrophin-4/5 binding
Alternate IDs
GO:0048404, GO:0048405
Definition
Binding to a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth. Source: GOC:jl
Comment
Note that mammalian NT-5 was initially named differently from amphibian NT-4 because of sequence differences, but the two genes were later shown to be functionally equivalent [SF:919858].
History
See term history for GO:0043121 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of neurotrophin binding (GO:0043121)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
neurotrophin binding [is_a relation] is_a  growth factor binding (GO:0019838)
Children of neurotrophin binding (GO:0043121)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
brain-derived neurotrophic factor binding (GO:0048403) [is_a relation] is_a  neurotrophin binding
nerve growth factor binding (GO:0048406) [is_a relation] is_a  neurotrophin binding
neurotrophin receptor activity (GO:0005030) [BFO:0000051 relation] BFO:0000051  neurotrophin binding
None.