Term Information

Accession
GO:0042771
Name
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
Ontology
biological_process
Synonyms
DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
Alternate IDs
None
Definition
The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage, and ends when the execution phase of apoptosis is triggered. Source: GOC:go_curators, GOC:mtg_apoptosis
Comment
None
History
See term history for GO:0042771 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:0042771)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [is_a relation] is_a  intrinsic apoptotic signaling pathway in response to DNA damage (GO:0008630)
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [is_a relation] is_a  intrinsic apoptotic signaling pathway by p53 class mediator (GO:0072332)
Children of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:0042771)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:1902166) [RO:0002212 relation] RO:0002212  intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:1902165) [RO:0002211 relation] RO:0002211  intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:1902167) [RO:0002213 relation] RO:0002213  intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
None.