Term Information

Accession
GO:0042287
Name
MHC protein binding
Ontology
molecular_function
Synonyms
major histocompatibility complex binding, major histocompatibility complex ligand
Alternate IDs
None
Definition
Binding to a major histocompatibility complex molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation. Source: GOC:jl
Comment
Note that this term does not include binding to the antigen peptide bound to the MHC protein, for this also annotate to 'peptide antigen binding ; GO:0042605' or one of its children.
History
See term history for GO:0042287 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of MHC protein binding (GO:0042287)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
MHC protein binding [is_a relation] is_a  signaling receptor binding (GO:0005102)
Children of MHC protein binding (GO:0042287)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
MHC class II protein binding (GO:0042289) [is_a relation] is_a  MHC protein binding
MHC class Ib protein binding (GO:0023029) [is_a relation] is_a  MHC protein binding
MHC class I protein binding (GO:0042288) [is_a relation] is_a  MHC protein binding
None.