Term Information

Accession
GO:0042092
Name
type 2 immune response
Ontology
biological_process
Synonyms
T-helper 2 type immune response, Th2 immune response
Alternate IDs
None
Definition
An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects. Source: PMID:20200518, ISBN:0781735149, PMID:18007680, GOC:add, PMID:18000958, PMID:20065995
Comment
None
History
See term history for GO:0042092 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of type 2 immune response (GO:0042092)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
type 2 immune response [is_a relation] is_a  immune response (GO:0006955)
Children of type 2 immune response (GO:0042092)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
T-helper 2 cell differentiation (GO:0045064) [BFO:0000050 relation] BFO:0000050  type 2 immune response
negative regulation of type 2 immune response (GO:0002829) [RO:0002212 relation] RO:0002212  type 2 immune response
T-helper 2 cell cytokine production (GO:0035745) [BFO:0000050 relation] BFO:0000050  type 2 immune response
positive regulation of type 2 immune response (GO:0002830) [RO:0002213 relation] RO:0002213  type 2 immune response
regulation of type 2 immune response (GO:0002828) [RO:0002211 relation] RO:0002211  type 2 immune response
None.