Term Information

Accession
GO:0039557
Name
suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity
Ontology
biological_process
Synonyms
inhibition of host IRF7 by virus, inhibition of host interferon regulatory factor-7 by virus, suppression by virus of host IRF7 activity, suppression by virus of host interferon regulatory factor 7 activity
Alternate IDs
None
Definition
Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by reducing the activity of IRF7 (interferon regulatory factor-7). IRF7 a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF7, which allows IRF7 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes. Source: PMID:16014964, PMID:11943871, PMID:19557165
Comment
This term is for annotation of viral proteins that counteract the host anti-viral innate immune response.
History
See term history for GO:0039557 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
Parents of suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity (GO:0039557)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity [is_a relation] is_a  suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039537)

This term has no children.

None.