Term Information

Accession
GO:0038157
Name
granulocyte-macrophage colony-stimulating factor signaling pathway
Ontology
biological_process
Synonyms
CSF2 signaling pathway, GM-CSF receptor signaling pathway, GM-CSF signaling pathway, granulocyte-macrophage colony-stimulating factor receptor signaling pathway, granulocyte-macrophage colony-stimulating factor signalling pathway
Alternate IDs
None
Definition
The series of molecular signals initiated by the binding of the cytokine granulocyte macrophage colony-stimulating factor (GM-CSF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. GM-CSF binds to a heterodimer receptor (CSF2R) consisting of an alpha ligand-binding subunit, and a common beta subunit that is shared with other cytokine receptors. Source: GOC:signaling, PMID:17027509, GOC:nhn
Comment
None
History
See term history for GO:0038157 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of granulocyte-macrophage colony-stimulating factor signaling pathway (GO:0038157)
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granulocyte-macrophage colony-stimulating factor signaling pathway [is_a relation] is_a  cytokine-mediated signaling pathway (GO:0019221)
Children of granulocyte-macrophage colony-stimulating factor signaling pathway (GO:0038157)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
granulocyte macrophage colony-stimulating factor receptor activity (GO:0004901) [BFO:0000050 relation] BFO:0000050  granulocyte-macrophage colony-stimulating factor signaling pathway
None.