Term Information

Accession
GO:0038134
Name
ERBB2-EGFR signaling pathway
Ontology
biological_process
Synonyms
EGFR-HER2 signaling pathway, ERBB2-EGFR signalling pathway
Alternate IDs
None
Definition
The series of molecular signals initiated by binding of a ligand to an epidermal growth factor receptor (EGFR/ERBB1) on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and EGFR. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as EGFR. Source: GOC:signaling, Reactome:R-HSA-1963589, PMID:16460914
Comment
None
History
See term history for GO:0038134 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of ERBB2-EGFR signaling pathway (GO:0038134)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ERBB2-EGFR signaling pathway [is_a relation] is_a  epidermal growth factor receptor signaling pathway (GO:0007173)
ERBB2-EGFR signaling pathway [is_a relation] is_a  ERBB2 signaling pathway (GO:0038128)

This term has no children.

None.