sequestering of TGFbeta from receptor via TGFbeta binding
Term Information
Accession
GO:0038105
Name
sequestering of TGFbeta from receptor via TGFbeta binding
Ontology
biological_process
Synonyms
extracellular sequestering of TGFbeta, extracellular sequestering of transforming growth factor-beta
Alternate IDs
None
Definition
Binding to a transforming growth factor-beta (TGFbeta) protein in the extracellular region, and inhibiting TGFbeta signaling by preventing TGFbeta from binding to its cell surface receptor.
Source:
GOC:signaling,
GOC:bf,
PMID:19855014
Comment
This term is for annotation of gene products that bind to TGFbeta. For gene products that tether the TGFbeta-containing latency complex to the extracellular matrix, but do not necessarily bind TGF-beta directly, consider instead annotating to 'sequestering of TGFbeta in extracellular matrix ; GO:0035583'.