Term Information

Accession
GO:0038104
Name
nodal receptor complex
Ontology
cellular_component
Synonyms
ActRIIB.ALK4.EGF-CFC complex
Alternate IDs
None
Definition
A protein complex containing at least a type II activin receptor, a type I activin receptor, and a coreceptor (EGF-CFC protein) such as Cripto or Cryptic. Nodal receptor complexes are capable of binding a nodal protein and transducing the signal into the cell. Source: GOC:signaling, PMID:15062104, GOC:bf, PMID:11024047
Comment
Nodal signals through activin receptors but (unlike activin) also requires EGF-CFC coreceptors (such as Cripto or Cryptic in mammals) to signal. This term is intended for receptor/co-receptor components and not a nodal-receptor complex.
History
See term history for GO:0038104 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of nodal receptor complex (GO:0038104)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nodal receptor complex [is_a relation] is_a  receptor complex (GO:0043235)

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None.