Planteome: Term Details for "NIK/NF-kappaB signaling" (GO:0038061)

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Term Information

Accession: GO:0038061
Name: NIK/NF-kappaB signaling
Ontology: biological_process
Synonyms: NIK/NF-kappaB signal transduction, NIK-IKK cascade, NIK-IKK kinase cascade, NIK-IKK signaling pathway, NIK-IKK-alpha cascade, NIK/NF-kappaB cascade, p52-dependent NF-kappaB signaling, non-canonical NF-KB signaling, noncanonical NF-kappaB signaling, noncanonical nuclear factor kappaB (NF-kappaB) pathway
Alternate IDs: None
Definition: The process in which a signal is passed on to downstream components within the cell through the NIK-dependent processing and activation of NF-KappaB. Begins with activation of the NF-KappaB-inducing kinase (NIK), which in turn phosphorylates and activates IkappaB kinase alpha (IKKalpha). IKKalpha phosphorylates the NF-Kappa B2 protein (p100) leading to p100 processing and release of an active NF-KappaB (p52). Source: GOC:signaling, PMID:15140882, GOC:vs, PMID:11239468, GOC:bf, GOC:mg2
Comment: None
History: See term history for GO:0038061 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to NIK/NF-kappaB signaling.; Link to all direct and indirect annotations to NIK/NF-kappaB signaling.; Link to all direct and indirect annotations download (limited to first 10,000) for NIK/NF-kappaB signaling.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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BFO:0000001 entity
BFO:0000003 occurrent
GO:0008150 biological_process
GO:0065007 biological regulation
BFO:0000015 process
GO:0009987 cellular process
GO:0005575 cellular_component
GO:0050789 regulation of biological process
GO:0050896 response to stimulus
GO:0007154 cell communication
GO:0110165 cellular anatomical entity
GO:0051716 cellular response to stimulus
GO:0050794 regulation of cellular process
GO:0023052 signaling
GO:0005622 intracellular anatomical structure
GO:0007165 signal transduction
GO:0035556 intracellular signal transduction
GO:0038061 NIK/NF-kappaB signaling
GO:0007250 activation of NF-kappaB-inducing kinase activity
GO:1901223 negative regulation of NIK/NF-kappaB signaling
GO:0004704 NF-kappaB-inducing kinase activity
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:1901222 regulation of NIK/NF-kappaB signaling

Parents of NIK/NF-kappaB signaling (GO:0038061)

subject	relation	object
NIK/NF-kappaB signaling	BFO:0000051	positive regulation of NF-kappaB transcription factor activity (GO:0051092)
NIK/NF-kappaB signaling	is_a	intracellular signal transduction (GO:0035556)

Children of NIK/NF-kappaB signaling (GO:0038061)

subject	relation	object
activation of NF-kappaB-inducing kinase activity (GO:0007250)	BFO:0000050	NIK/NF-kappaB signaling
negative regulation of NIK/NF-kappaB signaling (GO:1901223)	RO:0002212	NIK/NF-kappaB signaling
NF-kappaB-inducing kinase activity (GO:0004704)	BFO:0000050	NIK/NF-kappaB signaling
positive regulation of NIK/NF-kappaB signaling (GO:1901224)	RO:0002213	NIK/NF-kappaB signaling
regulation of NIK/NF-kappaB signaling (GO:1901222)	RO:0002211	NIK/NF-kappaB signaling

NIK/NF-kappaB signaling

Term Information

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Parents of NIK/NF-kappaB signaling (GO:0038061)

Children of NIK/NF-kappaB signaling (GO:0038061)

None.