Term Information

Accession
GO:0038045
Name
large latent transforming growth factor-beta complex
Ontology
cellular_component
Synonyms
LLC, large latent complex
Alternate IDs
None
Definition
A protein complex containing latency-associated proteins (LAPs), mature disulphide-linked dimeric TGF-beta, and latent TGF-beta binding proteins (LTBPs). TGF-beta is mostly secreted as part of the large latent complex, and must be subsequently released from the LLC in order to bind to cell surface receptors. Source: PMID:8680476, Reactome:R-HSA-177107, PMID:9805445, GOC:bf, PMID:2350783
Comment
None
History
See term history for GO:0038045 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of large latent transforming growth factor-beta complex (GO:0038045)
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large latent transforming growth factor-beta complex [is_a relation] is_a  protein-containing complex (GO:0032991)

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None.