Term Information

Accession
GO:0036317
Name
tyrosyl-RNA phosphodiesterase activity
Ontology
molecular_function
Synonyms
VPg unlinkase activity, Y-pUpN PDE activity, unlinkase activity, uridylylpolynucleotide-(5' P->O)- tyrosine phosphodiesterase activity
Alternate IDs
None
Definition
Catalysis of the hydrolysis of a 5' tyrosyl-RNA phosphodiester bond between a protein and RNA. In picornaviruses, this covalent bond connects VPg, a viral-encoded protein essential for RNA replication, to the 5' end of all nascent picornavirus genomes; it is cleaved from viral RNA prior to its engaging in protein synthesis. Source: GOC:sp, GOC:bf, PMID:22908287, PMID:21408223
Comment
None
History
See term history for GO:0036317 at QuickGO
Subset
None
Feedback
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Parents of tyrosyl-RNA phosphodiesterase activity (GO:0036317)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
tyrosyl-RNA phosphodiesterase activity [is_a relation] is_a  catalytic activity, acting on RNA (GO:0140098)
tyrosyl-RNA phosphodiesterase activity [is_a relation] is_a  phosphoric diester hydrolase activity (GO:0008081)

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None.