DNA annealing, RPA-dependent DNA rewinding, single-stranded DNA bubble rewinding
Alternate IDs
None
Definition
The process in which interchain hydrogen bonds between two single-stranded DNA (ssDNA) are reformed to regenerate double-stranded DNA (dsDNA). ssDNA is often bound and stabilized by proteins such as replication protein A (RPA) to form ssDNA bubbles. The bubbles can be rewound by ATP-dependent motors to reform base pairs between strands and thus dsDNA.
Source:PMID:22704558,
PMID:22759634,
PMID:22705370,
PMID:21078962