Term Information

Accession
GO:0036105
Name
peroxisome membrane class-1 targeting sequence binding
Ontology
molecular_function
Synonyms
class 1 mPTS binding, PEX19-dependent mPTS binding
Alternate IDs
None
Definition
Binding to a class I peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-dependent manner. Source: GOC:pm, PMID:17020786, PMID:14709540
Comment
Currently identified mPTSs vary greatly in length, and cannot be distinguished by primary structure analysis, suggesting that the peroxisomal sorting information is not contained within a specific amino acid sequence. There do however appear to be two classes of mPTSs: class 1 mPTSs that are bound by PEX19 and imported in a PEX19-dependent manner, and class 2 mPTSs that are not bound by PEX19 and mediate protein import independently of PEX19. The two classes cannot be defined based on their amino acid sequence.
History
See term history for GO:0036105 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of peroxisome membrane class-1 targeting sequence binding (GO:0036105)
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peroxisome membrane class-1 targeting sequence binding [is_a relation] is_a  peroxisome membrane targeting sequence binding (GO:0033328)

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