Term Information

Accession
GO:0035976
Name
transcription factor AP-1 complex
Ontology
cellular_component
Synonyms
AP-1 complex, AP1 complex, Activating protein 1 complex, transcription factor AP1 complex
Alternate IDs
None
Definition
A heterodimeric transcription factor complex composed of proteins from the c-Fos, c-Jun, activating transcription factor (ATF) or JDP families. The subunits contain a basic leucine zipper (bZIP) domain that is essential for dimerization and DNA binding. Jun-Fos heterodimers bind preferentially to a heptamer consensus sequence (TPA responsive element (TRE)), whereas Jun-ATF dimers bind the cyclic AMP responsive element (CRE) to regulate transcription of target genes. Source: GOC:BHF, GOC:bf, PMID:9069263, Wikipedia:AP-1_transcription_factor, PMID:20060892, GOC:rl
Comment
None
History
See term history for GO:0035976 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of transcription factor AP-1 complex (GO:0035976)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
transcription factor AP-1 complex [is_a relation] is_a  RNA polymerase II transcription regulator complex (GO:0090575)
Children of transcription factor AP-1 complex (GO:0035976)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
atf1-pcr1 complex (GO:1990243) [is_a relation] is_a  transcription factor AP-1 complex
None.