Term Information

Accession
GO:0035241
Name
protein-arginine omega-N monomethyltransferase activity
Ontology
molecular_function
Synonyms
protein arginine omega-N monomethylase activity, S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-Nomega-methyl-L-arginine-forming), type III protein arginine methyltransferase activity
Alternate IDs
None
Definition
Catalysis of the addition of a methyl group to either of the unmethylated terminal nitrogen atoms (also called omega nitrogen) in peptidyl-arginine to form an omega-N-G-monomethylated arginine residue. The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-Nomega-methyl-L-arginine. Source: PMID:14705965, EC:2.1.1.321, RESID:AA0069
Comment
Type III protein arginine methyltransferases catalyze the single methylation of one of the terminal nitrogen atoms of the guanidino group in an L-arginine residue within a protein. Unlike type I and type II protein arginine methyltransferases, which also catalyze this reaction, type III enzymes do not methylate the substrate any further.
History
See term history for GO:0035241 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of protein-arginine omega-N monomethyltransferase activity (GO:0035241)
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protein-arginine omega-N monomethyltransferase activity [is_a relation] is_a  protein-arginine N-methyltransferase activity (GO:0016274)

This term has no children.

EC
2.1.1.321
MetaCyc
2.1.1.124-RXN
RHEA
48100