Term Information

Accession
GO:0035098
Name
ESC/E(Z) complex
Ontology
cellular_component
Synonyms
Extra Sex Combs/Enhancer of Zeste complex, PRC2 complex
Alternate IDs
None
Definition
A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4. Source: PMID:12408864, GOC:sp, PMID:12408863, GOC:bf, PMID:20064375
Comment
None
History
See term history for GO:0035098 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of ESC/E(Z) complex (GO:0035098)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ESC/E(Z) complex [is_a relation] is_a  histone methyltransferase complex (GO:0035097)
ESC/E(Z) complex [is_a relation] is_a  PcG protein complex (GO:0031519)

This term has no children.

None.