Extra Sex Combs/Enhancer of Zeste complex, PRC2 complex
Alternate IDs
None
Definition
A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4.
Source:PMID:12408864,
GOC:sp,
PMID:12408863,
GOC:bf,
PMID:20064375