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DNA negative supercoiling activity

Term Information

Accession
GO:0034335
Name
DNA negative supercoiling activity
Ontology
molecular_function
Synonyms
DNA gyrase activity, DNA-gyrase activity
Alternate IDs
None
Definition
Catalytic introduction of negative supercoils into a DNA molecule or region thereof. In bacteria, negative supercoils are only introduced by DNA gyrase, a type II topoisomerase, but not all DNA gyrases are capable of introducing supercoils. In bacteria, the level of supercoiling varies widely between species and has been characterized properly in only a handful of organisms. The best characterized enzyme, from E.coli, is exceptionally proficient at supercoiling and this ability is not representative of all bacteria. Source: GOC:krc, WikiPedia:DNA_gyrase, GOC:mah, GOC:bhm
Comment
Note that this term was reinstated from obsolete.
History
See term history for GO:0034335 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of DNA negative supercoiling activity (GO:0034335)
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DNA negative supercoiling activity [is_a relation] is_a  DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (GO:0003918)

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None.