Term Information

Accession
GO:0033782
Name
24-hydroxycholesterol 7alpha-hydroxylase activity
Ontology
molecular_function
Synonyms
24-cholest-5-ene-3beta,24-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity, 24-hydroxycholesterol 7alpha-monooxygenase activity
Alternate IDs
None
Definition
Catalysis of the reaction: (24S)-hydroxycholesterol + O2 + reduced [NADPH-hemoprotein reductase] = (24S)-7alpha-dihydroxycholesterol + H+ + H2O + oxidized [NADPH-hemoprotein reductase]. Source: PMID:10748047, RHEA:46124, PMID:11013305
Comment
Formerly EC:1.14.13.99.
History
See term history for GO:0033782 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of 24-hydroxycholesterol 7alpha-hydroxylase activity (GO:0033782)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
24-hydroxycholesterol 7alpha-hydroxylase activity [is_a relation] is_a  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen (GO:0016712)

This term has no children.

EC
1.14.14.26
KEGG_REACTION
R07208
MetaCyc
1.14.13.99-RXN
RHEA
46124