Term Information

Accession
GO:0033781
Name
cholesterol 24-hydroxylase activity
Ontology
molecular_function
Synonyms
CYP46, CYP46A1, cholesterol 24-monooxygenase activity, cholesterol 24S-hydroxylase activity, cholesterol,NADPH:oxygen oxidoreductase (24-hydroxylating) activity, cytochrome P450 46A1
Alternate IDs
None
Definition
Catalysis of the reaction: cholesterol + H+ + NADPH + O2 = (24S)-24-hydroxycholesterol + H2O + NADP+. Source: EC:1.14.14.25, RHEA:22716
Comment
None
History
See term history for GO:0033781 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of cholesterol 24-hydroxylase activity (GO:0033781)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cholesterol 24-hydroxylase activity [is_a relation] is_a  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen (GO:0016709)

This term has no children.

EC
1.14.14.25
KEGG_REACTION
R07207
MetaCyc
1.14.13.98-RXN
Reactome
R-HSA-192061
RHEA
22716