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receptor internalization

Term Information

Accession
GO:0031623
Name
receptor internalization
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane. Source: GOC:signaling, PMID:19643732, GOC:bf, GOC:mah, PMID:15006537
Comment
None
History
See term history for GO:0031623 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of receptor internalization (GO:0031623)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
receptor internalization [is_a relation] is_a  receptor-mediated endocytosis (GO:0006898)
Children of receptor internalization (GO:0031623)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of receptor internalization (GO:0002091) [RO:0002212 relation] RO:0002212  receptor internalization
insulin receptor internalization (GO:0038016) [is_a relation] is_a  receptor internalization
B cell receptor internalization (GO:0036300) [is_a relation] is_a  receptor internalization
Wnt receptor internalization (GO:0038017) [is_a relation] is_a  receptor internalization
regulation of receptor internalization (GO:0002090) [RO:0002211 relation] RO:0002211  receptor internalization
receptor internalization involved in canonical Wnt signaling pathway (GO:2000286) [is_a relation] is_a  receptor internalization
regulation of signal transduction by receptor internalization (GO:0038009) [is_a relation] is_a  receptor internalization
neurotransmitter receptor internalization (GO:0099590) [is_a relation] is_a  receptor internalization
positive regulation of receptor internalization (GO:0002092) [RO:0002213 relation] RO:0002213  receptor internalization
G protein-coupled receptor internalization (GO:0002031) [is_a relation] is_a  receptor internalization
None.