Term Information

Accession
GO:0031427
Name
response to methotrexate
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase. Source: ISBN:0198506732, GOC:ef, GOC:mah
Comment
None
History
See term history for GO:0031427 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of response to methotrexate (GO:0031427)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
response to methotrexate [is_a relation] is_a  response to oxygen-containing compound (GO:1901700)
response to methotrexate [is_a relation] is_a  response to organic cyclic compound (GO:0014070)
response to methotrexate [is_a relation] is_a  response to organonitrogen compound (GO:0010243)
response to methotrexate [is_a relation] is_a  response to salt (GO:1902074)
Children of response to methotrexate (GO:0031427)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cellular response to methotrexate (GO:0071414) [is_a relation] is_a  response to methotrexate
None.