Term Information

Accession
GO:0031091
Name
platelet alpha granule
Ontology
cellular_component
Synonyms
platelet alpha-granule
Alternate IDs
None
Definition
A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG). Source: PMID:8467233
Comment
None
History
See term history for GO:0031091 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of platelet alpha granule (GO:0031091)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
platelet alpha granule [is_a relation] is_a  secretory granule (GO:0030141)
Children of platelet alpha granule (GO:0031091)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
platelet alpha granule membrane (GO:0031092) [BFO:0000050 relation] BFO:0000050  platelet alpha granule
platelet alpha granule lumen (GO:0031093) [BFO:0000050 relation] BFO:0000050  platelet alpha granule