Planteome logo

beta-catenin destruction complex

Term Information

Accession
GO:0030877
Name
beta-catenin destruction complex
Ontology
cellular_component
Synonyms
APC-Axin-1-beta-catenin complex, Axin-APC-beta-catenin-GSK3B complex, BDC, beta-catenin degradation complex, 23S APC complex
Alternate IDs
GO:0034747, GO:0034742
Definition
A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome. Source: PMID:14600025
Comment
Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.
History
See term history for GO:0030877 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
Parents of beta-catenin destruction complex (GO:0030877)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
beta-catenin destruction complex [is_a relation] is_a  catalytic complex (GO:1902494)
beta-catenin destruction complex [is_a relation] is_a  intracellular protein-containing complex (GO:0140535)

This term has no children.

None.