Term Information

Accession
GO:0030122
Name
AP-2 adaptor complex
Ontology
cellular_component
Synonyms
HA2, HA2 clathrin adaptor
Alternate IDs
None
Definition
A heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits, and links clathrin to the membrane surface of a vesicle, and the cargo receptors during receptor/clathrin mediated endocytosis. Vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC). Source: PMID:22022230, PMID:10611976, GOC:mah, PMID:21097499, PMID:24322426
Comment
None
History
See term history for GO:0030122 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
Parents of AP-2 adaptor complex (GO:0030122)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
AP-2 adaptor complex [is_a relation] is_a  clathrin adaptor complex (GO:0030131)
AP-2 adaptor complex [BFO:0000050 relation] BFO:0000050  clathrin coat of coated pit (GO:0030132)
AP-2 adaptor complex [is_a relation] is_a  plasma membrane protein complex (GO:0098797)
AP-2 adaptor complex [BFO:0000050 relation] BFO:0000050  clathrin coat of endocytic vesicle (GO:0030128)

This term has no children.

None.