Term Information

Accession
GO:0017054
Name
negative cofactor 2 complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A heterodimeric protein complex that can stably associate with TATA-binding protein on promoters, thereby preventing the assembly of transcription factors TFIIA and TFIIB and leading to repression of RNA polymerase II transcription. The two subunits, NC2alpha (Drap1) and NC2beta (Dr1), dimerize through histone fold domains of the H2A/H2B type present in the amino termini. Source: PMID:15574413
Comment
None
History
See term history for GO:0017054 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of negative cofactor 2 complex (GO:0017054)
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negative cofactor 2 complex [is_a relation] is_a  RNA polymerase II transcription repressor complex (GO:0090571)

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None.