Term Information

Accession
GO:0016790
Name
thiolester hydrolase activity
Ontology
molecular_function
Synonyms
thiolesterase activity
Alternate IDs
None
Definition
Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A. Source: EC:3.1.2.-
Comment
None
History
See term history for GO:0016790 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of thiolester hydrolase activity (GO:0016790)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
thiolester hydrolase activity [is_a relation] is_a  hydrolase activity, acting on ester bonds (GO:0016788)
Children of thiolester hydrolase activity (GO:0016790)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
3-isopropylbut-3-enoyl-CoA thioesterase activity (GO:0034946) [is_a relation] is_a  thiolester hydrolase activity
3-oxoacyl-CoA hydrolase activity (GO:0102327) [is_a relation] is_a  thiolester hydrolase activity
acyl-[acyl-carrier-protein] hydrolase activity (GO:0016297) [is_a relation] is_a  thiolester hydrolase activity
hydroxyacylglutathione hydrolase activity (GO:0004416) [is_a relation] is_a  thiolester hydrolase activity
3-oxo-myristoyl-ACP hydrolase activity (GO:0102574) [is_a relation] is_a  thiolester hydrolase activity
2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity (GO:0034869) [is_a relation] is_a  thiolester hydrolase activity
S-formylglutathione hydrolase activity (GO:0018738) [is_a relation] is_a  thiolester hydrolase activity
S-succinylglutathione hydrolase activity (GO:0050273) [is_a relation] is_a  thiolester hydrolase activity
3-oxo-myristoyl-CoA hydrolase activity (GO:0102150) [is_a relation] is_a  thiolester hydrolase activity
CoA hydrolase activity (GO:0016289) [is_a relation] is_a  thiolester hydrolase activity
glutathione thiolesterase activity (GO:0047951) [is_a relation] is_a  thiolester hydrolase activity
3-oxo-palmitoyl-ACP hydrolase activity (GO:0102576) [is_a relation] is_a  thiolester hydrolase activity
[citrate-(pro-3S)-lyase] thiolesterase activity (GO:0047778) [is_a relation] is_a  thiolester hydrolase activity
palmitoyl-(protein) hydrolase activity (GO:0008474) [is_a relation] is_a  thiolester hydrolase activity
2-oxoglutaryl-CoA thioesterase activity (GO:0034843) [is_a relation] is_a  thiolester hydrolase activity
3-oxo-dodecanoyl-ACP hydrolase activity (GO:0102575) [is_a relation] is_a  thiolester hydrolase activity
myristoyl-CoA hydrolase activity (GO:0102991) [is_a relation] is_a  thiolester hydrolase activity
EC
3.1.2.-